منابع مشابه
Transient residence and exposure times
The residence time measures the time spent by a water parcel or a pollutant in a given water body and is therefore widely used in environmental studies. The adjoint method introduced by Delhez et al. (2004) to compute this diagnostic is revised here to take into account the effect of the initialization and of the boundary conditions. In addition to the equation for the mean residence time, it i...
متن کاملUnsteady near wall residence times and shear exposure in model distal arterial bypass grafts.
Building on previous studies of unsteady flow within model distal bypass grafts we analyse the near wall residence times and shear exposure in a 45 degrees anastomosis under symmetrical and symmetry breaking geometric configurations. We define residence time as the minimum time for a particle to exit a spherical region and shear exposure as a temporal integral of the Huber-Henky-von-Mises crite...
متن کاملCorrelations in the sequence of residence times.
Sequences of residence times (RTs) associated with the escape from metastable states are observed in many fields. Here we study analytically and numerically the correlations among RTs for a bistable stochastic system driven by dichotomous noise. Our theory predicts an oscillatory behavior of the correlations with respect to the lag between RTs. Correlations vanish at all lags if the switching r...
متن کاملSimple Pharmacokinetic Model Based on Mean Residence Times to Predict Furosemide Exposure after Oral Doses
Oral bioavailability of furosemide is low (around 70%) even if a solution of 40 mg is given to healthy subjects. Sustained release formulations rendered even lower absorption of drug (one half of immediate release formulations). First pass metabolism in the stomach, slow dissolution of solid formulations in acidic media, and a narrow absorption window in the upper portion of the small intestine...
متن کاملA physiological view and structures of mean residence times.
The author's previous theoretical study described the determination of a physiologically realistic structure of a mean residence time of an intravenously administered drug (Ďurišová 2012). This study continues previous work and the aim is to determine physiologically realistic structures of mean residence times of a drug administered either orally (MRTpo) or intramuscularly (MRTim). The determi...
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ژورنال
عنوان ژورنال: Ocean Science
سال: 2006
ISSN: 1812-0792
DOI: 10.5194/os-2-1-2006